New Studies Find Psychedelics Highly Effective for Alcoholism
New studies show unprecedented success in the treatment of alcoholism with psychedelic therapy.
The psychedelic revolution in mental health has produced overwhelming scientific evidence demonstrating the great efficacy of psychedelics in the treatment of various mental health disorders. Now, several new studies involving the drugs ketamine and MDMA are showing significant promise in the treatment of alcoholism.
Dr. Ben Sessa is a psychiatrist and chief medical officer at Awakn Life Sciences, an English biotech company that is at the forefront of the research, development, and delivery of psychedelic medicines.
The company is especially focused on the treatment of Alcohol Use Disorder or AUD, given how prevalent and challenging it is to treat.
“Alcoholism is a huge public health problem. It’s also a psychiatric condition that’s very poorly treated with very poor outcomes with traditional methods,” Sessa said. “Relapse to drinking after getting dry is around 80 to 90 percent at 12 months. That’s an embarrassingly poor statistic. Psychedelics offer a completely new approach; they offer the patient to explore the root causes of addiction, which so often is trauma. Psychedelic-assisted psychotherapy is an intensive upfront piece of work that gets the patient better, so they don’t have to keep coming back. It is a completely different paradigm shift to the way we currently manage patients in maintenance therapies.”
A recent study conducted by researchers at the University of Exeter and Awakn Life Sciences is the world’s first to examine the use of ketamine to treat AUD in a randomized controlled trial.
“Ketamine is a very well-established human medicine. It is indeed the only psychedelic that’s licensed as a medicine, as an anesthetic medicine, and has been used since the 60s as such. It’s an incredibly safe medicine. When it’s used at a much lower dose, it produces an altered state of consciousness. What we do in psychedelic-assisted psychotherapy with ketamine, is we use this altered state of consciousness to affect a more effective and deeper form of psychotherapy. So, we’re using ketamine as an adjunct to psychotherapy to treat addictions,” he said.
Participants in the study had all just completed a medically supervised alcohol detox program. Those in the experimental group received treatment with both ketamine and a form of psychotherapy called KARE over the course of four weeks.
“The group that received ketamine and specific KARE psychotherapy led to an 86 percent abstinence rate at six months — absolutely blows out of the water the current best treatments for alcoholism,” Sessa said.
Just what accounts for these astounding results?
“So we know a fair bit about the mode of action of ketamine, you literally grow new brain tissue after taking ketamine,” Sessa said. “Now, this is hugely helpful because when you combine that — when you think of it as a super-ripe brain bristling with neuronal activity — with psychotherapy in which you are asking the patient to address the psychological issues that are usually around stuck, rigid narratives they hold, then you can grow this new neural tissue in the direction you want to have changes to their psychology. This is a huge breakthrough for addictions, which is so much about rigidity and stuck-ness.”
The implications of this groundbreaking study are truly profound.
“Once we get the drug actually licensed and approved for, specifically, alcohol-use disorder, it hugely broadens the accessibility and far more clinicians would be willing to be using this in a much broader way. So, it will really radically change the field of treatment of alcoholism all over the world,” he said.
In addition to their work with ketamine, Awakn has also recently completed a study with another psychoactive drug MDMA which has yielded equally significant findings.
Watch Pt. 2 of our interview with Dr. Ben Sessa:
Ayahuasca Study Shows Breakthrough in Resolving Intercultural Conflict
Can plant medicines heal long-standing, sociopolitical conflicts? A new study brought together groups with deep-rooted enmity for each other in an ayahuasca ceremony—could this be the solution for a more peaceful world?
Plant medicines, including ayahuasca and psilocybin from “magic mushrooms” have become breakthrough therapeutic modalities for treating depression, anxiety, and addiction, as taboos around psychedelics fade and scientists study their effects in sanctioned clinical settings. And now a group of scientists from the US, UK, and Israel has begun to look at ayahuasca as a tool for resolving intercultural conflict. By bringing together Israelis and Palestinians for a group ceremony, the researchers looked for signs of reconciliation and intergroup contact between the subjects.
Dr. Maya Shetreat MD, is a neurologist and herbalist specializing in plant medicine and psychedelic-assisted therapy. She had this to say about the recent study…
“We should definitely be able to experience significant shifts in identity politics because we know that psychedelic medicines like ayahuasca or psilocybin have these ego-dissolving properties that change the way our brains see us, see our identity, and perceive us as being separate from one another,” Dr. Shetreat said. “So, theoretically it’s possible that any kind of identity issues, whether it be political or otherwise, could be more in a place of resolution because people can see past differences.”
Results of this recent study proved to be profound, with several participants reporting visions in which they re-lived trauma from the perspective of those from the opposite culture. And in one instance, a participant was able to embody a single experience from both perspectives.
But while these results held significant weight for those involved, how does this translate at a larger scale?
“You know we have to ask the question, is it really necessary for everyone to be in ceremony and go through a psychedelic experience in order to create change? And actually, I think there’s an argument that it doesn’t take that many people, not everybody has to be in that role and enter that liminal space. The people who are called and the people who are motivated to engage with the medicine have those revelations, integrate, take action, and actually lead other people to see those connections that other people might not be able to see,” Dr. Shetreat said.
